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The Ministry of Health and Welfare is fast-tracking a Chinese medicine herbal formula that may help treat COVID-19. Many doctors of traditional Chinese medicine have developed formulas to treat the disease. One particular pill has proven results and is already sold abroad. Now Taiwan has a strict system when it comes to approving new drugs, but doctors say it may be available soon.  Ten kinds of Chinese medicinal ingredients are laid out. A doctor explains their uses. No cures are proven for COVID, but these ingredients form a Chinese medical formula called NRICM101 - shown to be an effective therapy.  Dr. Huang Chien-jung Taipei Chinese Medical Association NRICM101 contains several ingredients that clear internal heat and relieve fever. Basically it can be used to treat respiratory diseases with minor symptoms. The main active ingredients include fish mint and indigowoad root.  The new formula, developed at the National Research Institute of Chinese Medicine, also contains other common anti-inflammatory herbs such as Chinese skullcap. Gypsum and capillary wormwood are said to harmonize the immune system, while mulberry leaves, siler and Japanese catnip support the lungs’ bronchioles.  Dr. Huang Chien-jung Taipei Chinese Medical Association At the stage when the virus enters and infects the body, our innate immune system creates the body’s resistance. 

When our “killer T cells” are strong, Chinese medicine has a very pronounced effect on helping to strengthen this protection.  The formula has already gained permits to be sold in Europe and America. Taiwan’s tests for new drugs are very stringent and it’s not approved here yet. With COVID escalating, the Ministry of Health and Welfare convened to discuss an emergency fast-track of the process. Two producers have applied for temporary permits to make the formula.  Dr. Shih Chun-chuan Nat’l Union of Chinese Medical Doctors’ Assoc. There are clinical cases where the formula has been shown to reduce pulmonary infiltrates, and to reduce the length of time spent in hospital. We observed the course of treatment. So it can be of some help and that’s why the response was so good.  Many Chinese medicine doctors are responding to COVID. There are formulas for minor, moderate and severe symptoms, as well as for post-COVID recovery. But NRICM101 requires a prescription and cannot be sold online or by a pharmacist. There are also lots of fake medicines on the market with no demonstrable effects. Doctors warn to only go to reputable sources for your medicines.

COVID-19 is a global pandemic, with over 50 million confirmed cases and 1.2 million deaths as of November 11, 2020. No therapies or vaccines so far are recommended to treat or prevent the new coronavirus. A novel traditional Chinese medicine formula, Taiwan Chingguan Yihau (NRICM101), has been administered to patients with COVID-19 in Taiwan since April 2020. Its clinical outcomes and pharmacology have been evaluated. Among 33 patients with confirmed COVID-19 admitted in two medical centers, those (n = 12) who were older, sicker, with more co-existing conditions and showing no improvement after 21 days of hospitalization were given NRICM101. They achieved 3 consecutive negative results within a median of 9 days and reported no adverse events. Pharmacological assays demonstrated the effects of the formula in inhibiting the spike protein/ACE2 interaction, 3CL protease activity, viral plaque formation, and production of cytokines interleukin (IL)-6 and tumor necrosis factor (TNF)-α. This bedside-to-bench study suggests that NRICM101 may disrupt disease progression through its antiviral and anti-inflammatory properties, offering promise as a multi-target agent for the prevention and treatment of COVID-19. 

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